Chloroquine neuromyopathy associated with keratopathy and retinopathy.
نویسندگان
چکیده
منابع مشابه
[Chloroquine retinopathy].
Chloroquine Retinopathy refers to the changes seen in the retina of patients due to long term use of chloroquine. The late presentation, classically described as bull’s eye maculopathy, is preceded by a number of subtle changes. With the advent of new investigation modalities and regular screening, it is possible to prevent irreversible retinal damage due to this important and widely used drug....
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Delayed-onset chloroquine retinopathy was diagnosed in a patient seven years after cessation of treatment by a total dose of 730 g of chloroquine for rheumatoid arthritis. Visual functions continued to deteriorate after the diagnosis. Periodic examinations by ophthalmoscopy and by functional tests such as EOG and visual fields should be continued in patients at risk of delayed-onset chloroquine...
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ANTIMALARIAL drugs are used in the treatment of lupus erythematosus and have been used in the treatment of rheumatoid arthritis following the observation by Page (1951) of the beneficial effect on the joint symptoms of two patients who were taking mepacrine for chronic lupus erythematosus. Mepacrine was found to cause discoloration of the skin and agranulocytosis, so that chloroquine is now pre...
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This report describes presumed atypical hypoparathyroidism, deafness, and renal dysplasia (HDR) syndrome associated with unexpected ocular findings. The patient had exotropia, bilateral band keratopathy, and pigmentary retinopathy, including attenuated retinal vessels and atrophy of the retinal pigment epithelium. Even though the calcific plaques were successfully removed, visual acuity in both...
متن کاملChloroquine retinopathy in the rhesus monkey.
Chloroquine was administered intramuscularly 5 days a week to rhesus monkeys for as long as 4 1/2 years. No clinical, fluorescein angiographic, or electrophysiological evidence of retinal damage was observed. Yet chloroquine/chloroquine byproduct analysis of the ocular tissues revealed an enormous binding capacity of the pigmented tissues of the eye (choroid plus RPE, ciliary body, and iris) wi...
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ژورنال
عنوان ژورنال: BMJ
سال: 1967
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5546.219